Defences of Ph.D. Thesis/2004

Abroi Aare. The determinants for the native activities of the bovine papillomavirus type 1 E2 protein are separable. Ph.D. thesis 87., 2004, Tartu, Tartu University Press. Supervisor: Prof. Mart Ustav.

Kahre Tiina. Cystic fibrosis in Estonia.Ph.D. thesis 88.,2004,Tartu,Tartu University Press. Supervisor: Prof. Andres Metspalu.

Tambets Kristiina. Towards the understanding of post-glacial spread of human mitochondrial DNA haplogroups in Europe and beyond: a phylogeographic approach. Ph.D. thesis 92., 2004, Tartu, Tartu University Press. Supervisor: Prof. Richard Villems.

Peters Maire. Natural horizontal transfer of the pheBA operon. Ph.D. thesis 96., 2004, Tartu, Tartu University Press. Supervisor: Sen.scientist Allan Nurk (Tartu University, Institute of Technology)

Truu Jaak. Oil shale industry wastewater: impact on river microbial community and possibilities for bioremediation Ph.D. thesis 95., 2004, Tartu, Tartu University Press. Supervisor: Prof. Ain Heinaru.

Kadaja Lilian. Studies on modulation of the activity of tumor suppressor protein p53. Ph.D. thesis 94., 2004, Tartu, Tartu University Press. Supervisor: Prof. Toivo Maimets

Jõers Arvi. Regulation of p53-dependent transcription. Ph.D. thesis 93., 2004, Tartu, Tartu University Press. Supervisor: Prof. Toivo Maimets.

Maiväli Ülo. Studies on the structure-function relationship of the bacterial ribosome. Ph.D. thesis 97., 2004, Tartu, Tartu University Press. Supervisor: Prof. Jaanus Remme.

Rootsi Siiri. Human Y-chromosomal variation in European populations. Ph.D. thesis 102., 2004, Tartu, Tartu University Press. Supervisor: Prof. Richard Villems.

Defences of M.Sc. Thesis/2004

Kask Klaara. Õpetajate täiendkoolituse mõju õpilaste protsessuaalsete oskuste kujundamisele praktiliste tööde käigus. (The effect on in-service teacher education on students’ process skills through practical work). Supervisor: sen.scientist Miia Rannikmäe.

Puurand Tarmo. Rekombinatsioonipunktide jaotus inimese 19. ja 22. kromosoomis. (Distribution of recombinationspots in human chromoseomes 19 and 22). Supervisor: prof. Maris Laan.

Tegova Radi. DNA polümeraas IV osalus Pseudomonas putida rakkudes toimuvates mutatsiooniprotsessides. (Involvement of DNA polymerase IV in mutational processes in Pseudomonas putida cells). Supervisor: scientist Andres Tover, assoc. prof. Maia Kivisaar.

Putrinš Marta. Rakkude füsioloogilisest seisundist tulenevad kontrollmehhanismid Pseudomonas putida fenooli degradatsiooni operoni pheBA transkriptsiooni regulatsioonil. (Physiological control mechanisms of transcription of the phenol degradation operon pheBA in Pseudomonas putida) Supervisor: scientist Andres Tover, assoc.prof. Maia Kivisaar.

Meikar Oliver. Pseudomonas mandelii PC17 ja tema polühüdroksüalkanoaadi metabolism. (Pseudomonas mandelii PC17 and its polyhydroxyalkanoate metabolism) Supervisor: sen.scientist Allan Nurk.

Org Tõnis. DNA kiipide kasutamine proteinuursete haiguste uurimiseks. (Using microarrays to study proteinuric diseases) Supervisor: prof. Andres Metspalu.

Karitkina Diana. Escherichia coli 23S rRNA heeliks 69 roll ribosoomis. (The role of Escherichia coli 23 SrRNA helix 69 for the ribosome) Supervisor: prof. Jaanus Remme, sen.scientist Aivar Liiv.

Hääl Ingrid. Semliki Forest viiruse mittestruktuurseid valke ekspresseerivate rakuliinide konstrueerimine ja iseloomustamine. (The designing and characterization of cell lines expressing Semliki Forest Virus non-structural proteins) Supervisor: prof. Andres Merits.

Säälik Pille. Rakku penetreeruvate peptiidide valgutranspordi mehhanism, kineetika ja efektiivsus biotinüleeritud peptiidi ja avidiini kompleksi mudeli alusel. (Themechanism,kineticsandefficiencyof proteintransportof cellpenetrating peptides based on the model of biotinylated peptides and avidin) Supervisor: sen.scientist Margus Pooga, assoc.prof. Sulev Ingerpuu.

Suitso Indrek. Bacillus coagulans SIM-7 võrdlus kahe laktobatsilli tüvega piimhappe tootmisel. (Bacillus coagulans SIM-7 compared with two strains of lactobacilli for production of lactic acid) Supervisor: sen.scientist Allan Nurk.

Roostalu Urmas. Towards the understanding of the origin of human genetic variation in Eurasia: mtDNA haplogroup H in the Caucasus. Supervisor: prof. Richard Villems.

Janikson Kadri. Episomaalsete DNA viiruste replikatsiooni- ja segregatsioonifunktsiooni uurimine. (Studies of the replication and segregation functions of episomal DNA viruses) Supervisor: prof. Mart Ustav.

Hallast Pille. Geenikonversiooni roll lokaalsete alleelse aheldatuse (LD) mustrite kujundamises inimese genoomis kooriongonadotropiini beta subühiku (CGB) geeniperekonna näitel. (The role of gene conversion in shaping the local patterns of linkage disequilibrium in Human Chorionic gonadotropin beta-subunit gene family) Supervisor: prof. Maris Laan.

Sild Kristiina. Veise papilloomiviiruse tüüp 1 E2 valgu ja raku tuumastruktuuride vaheliste interaktsioonide uurimine. (In vivo association of the bovine papillomavirus E2 protein with nuclear structures) Supervisor: prof. Mart Ustav, sen.scientist Reet Kurg.

Serk Piia. Human mitochondrial DNA heplogroup J in Europe and Near-East. Supervisor: prof. Richard Villems, sen.scientist Ene Metspalu.

Värv Signe. P19ARF-I mõju p53-e märklaudgeenide transkriptsiooni aktivatsioonile. (The effect of p19 ARF on the regulation of transcription of p53 target genes) Supervisor: prof. Toivo Maimets, scientist Dina Lepik.

Jänes Jaak. FRET meetodi optimeerimine p53 ja Mdm2 valk-valk interaktsiooni detekteerimiseks. (Optimization of FRET method to detect protein-protein interaction of p53 and Mdm2) Supervisor: prof. Toivo Maimets, scientist Viljar Jaks.

Philips Mari-Anne. Geeniekspressiooni analüüs agressiivsete (SAL) ja mitteagressiivsete (LAL) hiirte hippokampuses subtraktiivse hübridisatsiooni meetodil. (The analysis of gene expression profiles in the hippocampus of aggressive (SAL) and nonaggressive (LAL) mice by subtractive hybridization) Supervisor: sen.scientist Sulev Kõks, prof. Andres Metspalu.

Nikonov Andrei. Specific monoclonal antibodies as tools for studying structure-function relationship of HCVRNA-dependent RNA-polymerase. Supervisor: prof. Mart Ustav.

Nelis Mari. Hingamis- ja seedeelundkonna ülemise osa kasvajatega seotud kandidaatgeenide polümorfismideassotsiatsioonuuring. (Association study of candidate gene polymorphisms involved in the susceptibility of upper aerodigestive tract cancers) Supervisor: prof. Andres Metspalu, prof. Maris Laan.

Geimanen Jelizaveta. Episomaalsete replitseeruvate hübriidsete origini sisaldavate vektorsüsteemide testimine koekultuuri tingimustes. (Cell culture testing of episomal origin-hybrid vector systems) Supervisor: sen.scientist Ene Ustav.

Männik Katrin. Inimese X kromosoomi spetsiifilise mikrokiibi väljatöötamine vaimse alaarenguga seotud DNA koopiaarvu submikroskoopiliste muutuste tuvastamiseks. (Development of human chromosome X-specificmicroarray for the detection of submicroscopic DNA copy number changes in case of mental retardation) Supervisor: assoc.prof. Ants Kurg.

Sõber Siim. Papilloomiviiruse L1 valgul põhinevate viiruslaadsete partiklite moodustamine. (Formation of virus like particles based on papillomavirus L1 protein) Supervisor: sen.scientist Reet Kurg.

Kivil Anri. Tuumor-supressor valgu p53 mõju veise papilloomiviiruse tüüp 1 replikatsioonile in vitro. (The effect of the tumor suppressor protein p53 to the replication of bovine papillomavirus type 1 in vitro) Supervisor: sen.scientist Ene Ustav.

Teppo Moonika. Grade nine students’ opinions relating to the relevance of science education. Supervisor: sen.scientist Miia Rannikmäe.